Chemotherapy Biotherapy Certification ONS Practice Testq

What does G-CSF primarily stimulate in the bone marrow?

1. Red blood cell production

2. White blood cell production

3. Platelet production

4. All cell lineages simultaneously

The correct answer is: White blood cell production

G-CSF, or Granulocyte-Colony Stimulating Factor, primarily stimulates the production of white blood cells, specifically neutrophils, in the bone marrow. It plays a crucial role in hematopoiesis by encouraging the bone marrow to increase the production and release of these immune cells into the bloodstream. This is particularly important in clinical settings where patients may be experiencing neutropenia due to chemotherapy, as G-CSF can help to mitigate the risk of infections by promoting a stronger immune response. In this context, while red blood cell and platelet productions are essential functions of the bone marrow, G-CSF does not specifically target or stimulate these processes. Instead, it is designed to enhance the production of granulocytes, a type of white blood cell, ensuring that the body can adequately defend itself against infections, especially after treatment that can lead to decreased white blood cell counts. Therefore, understanding the specific role of G-CSF is vital for healthcare professionals managing patients undergoing treatments that impact their immune system.